THE SVO(2) STUDY - GENERAL DESIGN AND RESULTS OF THE FEASIBILITY PHASE OF A MULTICENTER, RANDOMIZED TRIAL OF 3 DIFFERENT HEMODYNAMIC APPROACHES AND 2 MONITORING TECHNIQUES IN THE TREATMENT OF CRITICALLY ILL PATIENTS
Anno:
1995
Rivista: CONTROLLED CLINICAL TRIALS
Autori/autrici: Brazzi, L; Gattinoni, L; Latini, R; Tognoni, G; Decarli, A; Loi, U; Suter, P; Volpi, A; Borelli, M; Foti, G; Fumagalli, R; Liberati, A; Pesenti, A; Tinazzi, A; Torri, V; Dambrosio, N; Scarcia, C; Pietropaoli, P; Donati, Abele; Buoncristiano, U; Cardona, S; Feri, M; Capria, V; Cinnella, G; Brienza, A; Malacrida, R; Nastasi, M; Campagna, S; Alati, G; Delmonte, D; Fiorini, M; Gallo, F; Valenti, S; Pappagallo, S; Tulli, G; Maitan, S; Pezzi, G; Iscra, F; Gullo, A; Giordano, F; Desilvestre, A; Baldassarre, M; Sorgona, F; Bertasso, Cl; Zoccali, G; Torelli, V; Lacquaniti, L; Digito, A; Mendez, N; Basilico, E.
Lingua: ENG
Classificazione IRIS: 1.1 Articolo in rivista
Scheda completa IRIS: https://iris.univpm.it/handle/11566/39486
Citazioni:THE SVO(2) STUDY - GENERAL DESIGN AND RESULTS OF THE FEASIBILITY PHASE OF A MULTICENTER, RANDOMIZED TRIAL OF 3 DIFFERENT HEMODYNAMIC APPROACHES AND 2 MONITORING TECHNIQUES IN THE TREATMENT OF CRITICALLY ILL PATIENTS / Brazzi, L., Gattinoni, L., Latini, R., Tognoni, G., Decarli, A., Loi, U., Suter, P., Volpi, A., Borelli, M., Foti, G., Fumagalli, R., Liberati, A., Pesenti, A., Tinazzi, A., Torri, V., Dambrosio, N., Scarcia, C., Pietropaoli, P., Donati, A., Buoncristiano, U., et al.. - In: CONTROLLED CLINICAL TRIALS. - ISSN 0197-2456. - 16:(1995), pp. 74-87.
Abstract:Abstract: Although the attainment of normal hemodynamic values has always been assumed to be the therapeutic target for critically ill patients, recent studies reported increased values in oxygen transport varia bles in survivors of high-risk surgery. It has been supposed that the higher values obse
...rved in survivors might indicate a physiological compensation for the increased metabolic requirements due to disease. We designed a randomized, multicentric trial to evaluate the effect of high values of cardiac index(CI) and oxygen delivery (DO2) in critically ill patients. Patients enrolled in the study are randomized to three different hemodynamic targets:normal values of CI (2.5 < CI < 3.5 L min m, and mixed venous oxygen saturation (SvO2) > 70% or (Sata-Satv) < 20%. Two different monitoring systems are used to maintain the target: conventional Swan-Ganz catheter with scheduled samples of mixed venous O2 saturation, and optical catheter with continuous SvO2 evaluation. The aim of the...
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